A Simple Model to Identify Risk of Sarcopenia and Physical Disability in HIV-Infected Patients

作者: Paulo Farinatti , Lorena Paes , Elizabeth A. Harris , Gabriella O. Lopes , Juliana P. Borges

DOI: 10.1519/JSC.0000000000002070

关键词: SurgeryCircumferenceMuscle lossBody mass indexIn patientMedicineHiv infected patientsKnee extensionModel validityNuclear medicineSarcopenia

摘要: Farinatti, P, Paes, L, Harris, EA, Lopes, GO, and Borges, JP. A simple model to identify risk of sarcopenia physical disability in HIV-infected patients. J Strength Cond Res 31(9): 2542-2551, 2017-Early detection might help preventing muscle loss This study proposed a for estimating appendicular skeletal mass (ASM) calculate indices "sarcopenia" (SA) "risk due sarcopenia" (RSA) patients with HIV. An equation estimate ASM was developed 56 (47.2 ± 6.9 years), cross-validation sample 24 (48.1 6.6 years). The validity determined by calculating, both samples: (a) Concordance between actual vs. estimated ASM; (b) Correlations actual/estimated peak torque (PT) total work (TW) during isokinetic knee extension/flexion; (c) Agreement classified SA RSA. predictive (kg) = 7.77 (sex; F 0/M 1) + 0.26 (arm circumference; cm) 0.38 (thigh 0.03 (Body Mass Index; kg·m) - 8.94 (R 0.74; Radj 0.72; SEE 3.13 kg). confirmed validation (t 0.081/p 0.94; R 0.86/p < 0.0001) 0.12/p 0.92; 0.87/p samples. Regression characteristics (Radj 0.80; 3.65) PRESS (RPRESS 0.69; SEEPRESS 3.35) were compatible the original model. Percent agreements classification RSA from calculated using 87.5% 77.2% (gamma correlations 0.72-1.0; p 0.04) validation, 95.8% 75.0% 0.98-0.97; 0.001) sample, respectively. PT (range 0.50-0.73, ≤ 0.05) TW 0.59-0.74, similar In conclusion, our correctly determine identifying

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