Is hepatitis C virus eradication around the corner only 25 years after its discovery

作者: Giuseppe Ippolito , Maria Rosaria Capobianchi , Simone Lanini , Guido Antonelli

DOI: 10.1016/J.IJANTIMICAG.2014.09.001

关键词: ImmunologyInterferonHepatitis C virusVirologyAntiviral therapyVirological responseRibavirinDiseaseChronic hepatitisMedicine

摘要: Hepatitis C virus (HCV), identified approximately 25 years ago, is recognised as the cause of several clinical conditions besides chronic hepatitis. New compounds with direct antiviral activity have recently been introduced. These drugs promise to outdo old therapies based on interferon and ribavirin both in terms improved safety virological response. In fact, these may pave way complete eradication disease. However, their actual price exceedingly high a strategy necessary guarantee wide sustainable access new therapies.

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