Ethacridine lactate -- a safe and effective drug for termination of pregnancy.

摘要: In India physicians analyzed data on 56 women (18-20 weeks gestation) at the Marie Stopes Clinic in Jodhpur who underwent pregnancy termination to evaluate efficacy and safety of ethacriding lactate which has antiseptic properties. They injected 150 cc 0.1% into intrauterine extra-amniotic space. used iv infusion oxytocin expedite delivery abortus. 59% cases were unmarried teenagers. Ethacridine induced successful abortion 92.8% (52) was much higher than that found literature (about 82%). Abortion failure occurred other 4 because transverse lie fetus (2) cervical dystocia (1) uterine inertia (1). The would have experienced regardless uterotonic abortifacient used. 3 evacuation while hysterotomy. Most (73.2%) 12-24 hours after induction. mean interval 20.1 house shorter previous reports (29.5-38 hours). shortest induction-abortion 10.5 longest more 36 hours. Complications 6 (14.4%) cases. (5.4%) suffered from tear. incomplete expulsion lower reported (16-30%). On hand 5.4% rate for prostaglandin hypertonic saline. There 1 case each severe bleeding vaginal laceration. properties ethacridine likely accounted complete absence sepsis these women. conclusion performs better instillation methods it is a safe effective method.