作者: Mark J. Ratain , Anna Di Rienzo , Carrie Grimsley , Federico Innocenti
DOI:
关键词: Irinotecan 、 Ugt1a1 gene 、 Bioinformatics 、 Genotype 、 Linkage disequilibrium 、 Toxicity 、 Cancer 、 Medicine
摘要: The present invention concerns the methods and compositions for evaluating risk of ironotecan toxicity in a cancer patient based on genotype at position −3156 UGT1A1 gene or any linkage disequilibrium with variant.