Methods for predicting irinotecan toxicity

作者: Mark J. Ratain , Anna Di Rienzo , Carrie Grimsley , Federico Innocenti

DOI:

关键词: IrinotecanUgt1a1 geneBioinformaticsGenotypeLinkage disequilibriumToxicityCancerMedicine

摘要: The present invention concerns the methods and compositions for evaluating risk of ironotecan toxicity in a cancer patient based on genotype at position −3156 UGT1A1 gene or any linkage disequilibrium with variant.

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