Methods for identifying ligands using competitive binding 1H NMR experiments
作者： Brian J. Stockman , Claudio Dalvit
DOI:
关键词: Molecule 、 Test sample 、 Proton NMR 、 Competitive binding 、 Ligand 、 Combinatorial chemistry 、 Chemistry
摘要: A method of identifying a ligand to target molecule that includes: providing reference compound interacts with the molecule; collecting 1 D H nuclear magnetic resonance spectrum in presence plurality test samples, each sample including at least one compound; and comparing determine change or more resonances; molecule, wherein displaces compound.
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