Electrochemical analyte measurement system

摘要: A small diameter flexible electrode designed for subcutaneous in vivo amperometric monitoring of glucose is described. The to allow "one-point" calibration, i.e., have zero output current at concentration, even the presence other electroreactive species serum or blood. preferably three four-layered, with layers serially deposited within a recess upon tip polyamide insulated gold wire. first concentration-to-current transducing layer overcoated an electrically insulating and flux limiting (second layer) on which, optionally, immobilized interference-eliminating horseradish peroxidase based film (third layer). An outer (fourth) biocompatible.