Immunological characterization of purified anti-haemophilic factor A (factor VIII) which corrects abnormal platelet retention in Von Willebrand's disease.
作者： B. N. BOUMA , Y. WLEGERINCK , J. J. SIXMA , J. A. VAN MOURIK , I. A. MOCHTAR
关键词: Von willebrand 、 Cryoprecipitate 、 Fibrinogen 、 Molecular biology 、 In vitro 、 Abnormal Platelet 、 Chemistry
摘要: ABNORMAL platelet retention in a column of glass beads, which has been described cases Von Willebrand's disease (VWD)1–6, is corrected vitro by cryoprecipitate prepared from normal plasma and partially purified factor VIII concentrates6–9 although fibrinogen ineffective (unpublished results). This suggests that responsible for the correction. We now have further evidence to support this suggestion.
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