Prophylactic antibiotics and wound infections following laminectomy for lumber disc herniation.

摘要: ✓ The authors review 531 consecutive operations for lumbar disc herniation performed on 496 patients by one neurosurgeon to determine the effect of prophylactic antibiotics upon postoperative wound infections. In this retrospective analysis 16 instances sepsis were found, 11 considered be major and five minor. 128 cases in which no antibacterial agents given, 1 minor infection occurred. Four infections developed 402 occasions when given perioperative period. Men had a significantly greater risk developing than women. These data suggest that pre- antibiotic therapy directed at narrow spectrum microorganisms reduced incidence significant undergoing laminectomy herniation.