Preparation and characterization of paclitaxel-loaded DSPE-PEG-liquid crystalline nanoparticles (LCNPs) for improved bioavailability.

作者: Ni Zeng , Quanyin Hu , Zhongyang Liu , Xiaoling Gao , Rongkuan Hu

DOI: 10.1016/J.IJPHARM.2011.12.058

关键词: Chemical engineeringDrug carrierEthylene glycolChromatographyNanocarriersNanoparticlePolarized light microscopyBioavailabilityTransmission electron microscopyHexagonal phaseChemistry

摘要: … Base on the similar structure and physicochemical properties between P80 and DSPE-PEG, here we hypothesized that DSPE-PEG might act as an alternative to P80 for serving as a …

参考文章(59)
Luciane H Gargaglioni, Vanessa Souza‐Moreno, Raphael E Szawka, Janete A Alselmo‐Franci, Kenia C Bicego, None, Serotonergic neurotransmission in the locus coeruleus modulates hypercapnic ventilatory response The FASEB Journal. ,vol. 23, pp. 1- ,(2009)
Jayesh R. Bellare, M. A. Arunagirinathan, Giddi Hema Sagar, Self-assembled surfactant nano-structures important in drug delivery: a review. Indian Journal of Experimental Biology. ,vol. 45, pp. 133- 159 ,(2007)
Maurie Markman, Alexander Kennedy, Kenneth Webster, Barbara Kulp, Gertrude Peterson, Jerome Belinson, Paclitaxel-Associated Hypersensitivity Reactions: Experience of the Gynecologic Oncology Program of the Cleveland Clinic Cancer Center Journal of Clinical Oncology. ,vol. 18, pp. 102- 105 ,(2000) , 10.1200/JCO.2000.18.1.102
R B Weiss, R C Donehower, P H Wiernik, T Ohnuma, R J Gralla, D L Trump, J R Baker, D A Van Echo, D D Von Hoff, B Leyland-Jones, Hypersensitivity reactions from taxol. Journal of Clinical Oncology. ,vol. 8, pp. 1263- 1268 ,(1990) , 10.1200/JCO.1990.8.7.1263
Ben J. Boyd, Darryl V. Whittaker, Shui-Mei Khoo, Greg Davey, Hexosomes formed from glycerate surfactants—Formulation as a colloidal carrier for irinotecan International Journal of Pharmaceutics. ,vol. 318, pp. 154- 162 ,(2006) , 10.1016/J.IJPHARM.2006.03.010
Gopal Garg, Shailendra Saraf, Swarnlata Saraf, Cubosomes : An overview Biological & Pharmaceutical Bulletin. ,vol. 30, pp. 350- 353 ,(2007) , 10.1248/BPB.30.350
C. Maechling-Strasser, Ph. Déjardin, J. C. Galin, A. Schmitt, Preadsorption of polymers on glass and silica to reduce fibrinogen adsorption Journal of Biomedical Materials Research. ,vol. 23, pp. 1385- 1393 ,(1989) , 10.1002/JBM.820231202
Richard T. Liggins, W.L. Hunter, Helen M. Burt, Solid-State Characterization of Paclitaxel Journal of Pharmaceutical Sciences. ,vol. 86, pp. 1458- 1463 ,(1997) , 10.1021/JS9605226