Predictors of late development of heart failure in stable survivors of myocardial infarction: the CARE study.

摘要: Abstract Objectives We sought to determine the predictors of heart failure (HF) development in long-term survivors myocardial infarction (MI). Background Modern strategies acute MI care have resulted an increasing proportion at heightened risk future non-fatal events, including HF. Methods assessed developing HF 3,860 stable patients without a previous history HF, who were enrolled Cholesterol And Recurrent Events (CARE) trial median 10 months post MI. Baseline characteristics did or not develop during five years observation assessed. Results A total 243 (6.3%) developed linear pattern rate 1.3%/year. Heart markedly increased death (hazard ratio 10.2, 95% confidence interval 7.7 13.5). Fifty-seven (23.5%) had recurrent between enrollment and onset fivefold. The most important age left ventricular ejection fraction. Other included diabetes, hypertension, MI, baseline rate. Moderate exercise three more times per week was independently associated with 30% lower Conclusions occurs time-dependent fashion, which is usually direct consequence detectable interim Patients experience late-onset 10-fold compared other survivors. can stratify high subsequent