Interspecies comparison of carcinogenic potency

作者: Edmund Crouch , Richard Wilson

DOI: 10.1080/15287397909529817

关键词: Risk analysis (engineering)Animal dataBiotechnologyCarcinogen ScreeningCarcinogenic potencyBiologyToxicologyPollution

摘要: For guidance in decisions on how to safeguard humans from carcinogens, it is necessary use data carcinogenesis animals. This paper discusses such data, combined with human experience, may be used quantitatively decisions. It demonstrated empirically that good correlations exist between different species for suitably defined carcinogenic potencies various chemicals. allows sufficient accuracy extrapolating animal risk support a logical scheme the evaluation of risks. Some recommendations future research are given.

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