Surgical treatment of early oral carcinoma—Results of a prospective controlled multicenter study
作者： Markus Wolfensberger , Peter Zbaeren , Pavel Dulguerov , Werner Müller , André Arnoux
DOI: 10.1002/HED.1073
关键词: Epidermoid carcinoma 、 Neck dissection 、 Prospective cohort study 、 Carcinoma 、 Oral Cavity Carcinoma 、 Medicine 、 Surgery 、 Stage (cooking) 、 Survival analysis 、 Radiation therapy
摘要: Purpose of the study. To assess whether early stage (pT1-2,pN0-1) oral cavity carcinoma is adequately treated by radical surgical resection alone. Material and Methods. Prospective multicenter Of 105 patients with cT1-2 cN0-1 in conformity study design, 12 had to be excluded because tumor- positive margins or pN >N1. The remaining 93 were monitored for at least 2 years. Results. Seventeen local regional recurrence develop. In 17 locoregional control was achieved second treatment. Overall, 4-year disease- specific survival probability 94%. Patients initially without selective neck dissection significantly higher recur- rence rates than those dissection, although not adversely affected. Conclusions. Early (pT1-2, pN0-1) squamous cell carci- noma surgery alone, provided are tumor free. On basis presented data, we would also advocate routine dissection. © 2001 John Wiley & Sons, Inc. Head Neck 23: 525-530, 2001.
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