Beagle Dog Pulmonary Surfactant Lipids

作者: Raymond C. Pfleger

DOI: 10.1001/ARCHINTE.1971.00310170071010

关键词: BeagleSalineLung tissueCholesterolAlkylMedicineLipid compositionCellPulmonary surfactantAnatomyChromatography

摘要: The lipids from normal beagle dog lungs, pulmonary surfactant, and exfoliated lining cells were quantitated by established procedures. surfactant obtained endobronchial saline lavage. Phospholipids accounted for more than 70% of the cell lipids: phosphatidyl choline was predominant phosphatide. Phosphatidyl glycerol is present in (10% phospholipid-P), (7% phospholipid-P) lung tissue (3% phospholipid-P). Cholesterol its esters 60% neutral lipid fractions. Alkyl alk-1-enyl ethers phospholipids all samples.

参考文章(32)
Nikola Z. Stanacev, Ying-Ying Chang, Eugene P. Kennedy, Biosynthesis of Cardiolipin in Escherichia coli Journal of Biological Chemistry. ,vol. 242, pp. 3018- 3019 ,(1967) , 10.1016/S0021-9258(18)99608-0
Gerald B. Dermer, The fixation of pulmonary surfactant for electron microscopy Journal of Ultrastructure Research. ,vol. 27, pp. 88- 104 ,(1969) , 10.1016/S0022-5320(69)90021-5
Julian Kanfer, Eugene P. Kennedy, METABOLISM AND FUNCTION OF BACTERIAL LIPIDS. II. BIOSYNTHESIS OF PHOSPHOLIPIDS IN ESCHERICHIA COLI. Journal of Biological Chemistry. ,vol. 239, pp. 1720- 1726 ,(1964) , 10.1016/S0021-9258(18)91247-0
George Rouser, A. N. Siakotos, Sidney Fleischer, Quantitative analysis of phospholipids by thin-layer chromatography and phosphorus analysis of spots. Lipids. ,vol. 1, pp. 85- 86 ,(1966) , 10.1007/BF02668129
G.M. Gray, THE ISOLATION OF PHOSPHATIDYL GLYCEROL FROM RAT-LIVER MITOCHONDRIA. Biochimica et Biophysica Acta. ,vol. 84, pp. 35- 40 ,(1964) , 10.1016/0926-6542(64)90098-8
Ewald R. Weibel, Joan Gil, Electron microscopic demonstration of an extracellular duplex lining layer of alveoli. Respiration Physiology. ,vol. 4, pp. 42- 57 ,(1968) , 10.1016/0034-5687(68)90006-6
W. S. Tyler, A. G. E. Pearse, Oxidative Enzymes of the Interalveolar Septum of the Rat Thorax. ,vol. 20, pp. 149- 152 ,(1965) , 10.1136/THX.20.2.149
S. I. Said, R. M. Klein, L. W. Norrell, Y. T. Maddox, Metabolism of alveolar cells: histochemical evidence and relation to pulmonary surfactant. Science. ,vol. 152, pp. 657- 659 ,(1966) , 10.1126/SCIENCE.152.3722.657
T. N. FINLEY, Bronchopulmonary Lavage in Normal Subjects and Patients with Obstructive Lung Disease Annals of Internal Medicine. ,vol. 66, pp. 651- 658 ,(1967) , 10.7326/0003-4819-66-4-651
R.C. Pfleger, A.J. Wilson, R.G. Cuddihy, R.O. McClellan, Bronchopulmonary Lavage for Removal of Inhaled Insoluble Materials from the Lung Diseases of the Chest. ,vol. 56, pp. 524- 530 ,(1969) , 10.1378/CHEST.56.6.524