Gastric mucosa-associated lymphoid tissue lymphoma.

摘要: The connection between Helicobacter pylori and gastric mucosa-associated lymphoid tissue (MALT) lymphoma is well established. H. infection causes an immunological response, leading to chronic gastritis with formation of follicles within the stomach. These resemble nodal tissues found throughout body are composed reactive T cells activated plasmal B cells. responsible for initiating a clonal expansion centrocyte-like that form basic histology MALT lymphoma. Early diagnosis difficult but essential adequate treatment. Clinical symptoms vague varied, abdominal pain being common presenting complaint. endoscopic appearance this tumor varied can be infiltrative, exophytic, or ulcerative. In addition, have multifocal distribution, therefore aggressive sampling crucial diagnosis. Endoscopic ultrasound document extent disease more accurate than CT scan in detection spread perigastric lymph nodes. Lesions confined mucosa submucosa wall believed dependent on stimulation successfully treated eradication. Those lymphomas present at advanced stages require management surgical resection, radiation, chemotherapy. Follow-up critical all patients who been eradication consists multiple biopsies histological molecular studies as 3, 6, 12 months after reappearance has seen years treatment, follow-up these should indefinite.