Contemporary model for cardiovascular risk prediction in people with type 2 diabetes

作者: Andre Pascal Kengne , Anushka Patel , Michel Marre , Florence Travert , Michel Lievre

DOI: 10.1177/1741826710394270

关键词: Proportional hazards modelFramingham Risk ScoreVascular diseaseCohortRandomized controlled trialMedicineDiabetes mellitusCardiologyInternal medicineIntensive care medicineType 2 diabetesDisease

摘要: Background: Existing cardiovascular risk prediction equations perform non-optimally in different populations with diabetes. Thus, there is a continuing need to develop new that will reliably estimate disease (CVD) and offer flexibility for adaptation various settings. This report presents contemporary model predicting people type 2 diabetes mellitus.Design methods: A 4.5-year follow-up of the Action Diabetes Vascular disease: preterax diamicron-MR controlled evaluation (ADVANCE) cohort was used coefficients significant predictors CVD using Cox models. Similar models were fit 4-year 7168 participants without previous CVD. The model’s applicability tested on same sample another dataset.Results: total 473 major events recorded during follow-up. Age at diagnosis, known duration diabetes, sex, pulse pressure, treated hypertension, atrial fib...

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