Postoperative adjuvant chemotherapy for resectable cholangiocarcinoma

作者: Vor Luvira , Egapong Satitkarnmanee , Ake Pugkhem , Chumnan Kietpeerakool , Pisake Lumbiganon

DOI: 10.1002/14651858.CD012814

关键词: Adjuvant chemotherapySurgeryGeneral surgeryMedicineResectable Cholangiocarcinoma

摘要: Background Cholangiocarcinoma (cancer in the bile duct) is an aggressive tumour for which surgical resection is a mainstay of treatment. Despite complete resection, recurrences of the cancer are common and lead to poor prognosis in patients. Postoperative adjuvant chemotherapy given after surgical resection may reduce the risk of cancer recurrence by eradicating residual cancer and micrometastatic lesions. The benefits and harms of postoperative adjuvant chemotherapy versus placebo, no intervention, or other adjuvant …

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