STRUCTURE OF THE REPLICATION ORIGINS OF PLASMIDS RK2 AND R6K AND THE REGULATION OF PLASMID DNA REPLICATION
作者： Donald R. Helinski , Manabu Inuzuka , Noriko Inuzuka , Roberto Kolter , David M. Stalker
DOI: 10.1016/B978-0-12-048850-6.50034-X
关键词: T-DNA Binary system 、 Genome 、 Molecular biology 、 Genetics 、 Base pair 、 Autonomously replicating sequence 、 Origin of replication 、 Direct repeat 、 Plasmid 、 Biology 、 Extrachromosomal DNA
摘要: ABSTRACT Regions of the plasmid genome essential for replication and maintenance in Escherichia coli have been identified two antibiotic resistance Plasmids, RK2 R6K. In both cases a small segment plasmid, containing an origin replication, has maintained as extrachromosomal element when another region(s) that specifies trans-acting product is present host cell. Nucleotide sequence analysis regions plasmids R6K revealed seven 22 base pair (bp) direct repeats tandem region eight 17 bp clusters three five RK2. A model presented involving interacting π protein, required initiation with necessary step replication.
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