Comparative efficacy of flubendazole chewable tablets and a tablet combination of febantel, pyrantel embonate and praziquantel against Trichuris vulpis in experimentally infected dogs.

摘要: Fourteen of 23 dogs developing patent Trichuris vulpis infections by 120 days p.i. with 5000 embryonated eggs were allocated into three groups. One group was treated flubendazole 220 mg chewable tablets (Flubenol) at the recommended dose regimen once daily for 3 days. The second given single treatment a tablet containing 150 febantel, 144 pyrantel embonate and 50 praziquantel in combination (Drontal Plus). third remained untreated. All necropsied worm counts 10 or 11 after (first) treatment. No worms recovered from resulting significant count reduction 100%. In contrast, 2 5 animals infected; geometric mean burden reduced 99.4% as compared to control but did not differ significantly those controls.