The Major Histocompatibility System of the Guinea Pig

作者: A. F. Geczy , A. L. De Weck

DOI: 10.1007/978-3-642-95293-7_6

关键词: Immune systemImmune response genesMajor histocompatibilityInbred strainImmunologyGuinea pigAntigenSerologyBiologyMixed lymphocyte reaction

摘要: The investigation of guinea pig leukocyte antigens has lagged considerably behind the first documented reports mouse (Gorer 1936) and human (Dausset 1958) antigens. Although been used extensively in a wide variety immunological studies, particularly for investigations genetic control immune response its relationship to histocompatibility-linked genes (McDevitt Benacerraf 1969), until recently, relatively little effort invested into serological aspects major histocompatibility system (MHS) this species.

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