The IL-1-Like Cytokine IL-33 Is Constitutively Expressed in the Nucleus of Endothelial Cells and Epithelial Cells In Vivo: A Novel ‘Alarmin’?

作者: Christine Moussion , Nathalie Ortega , Jean-Philippe Girard

DOI: 10.1371/JOURNAL.PONE.0003331

关键词: Immune systemImmunologyBiologyHigh endothelial venulesInterleukin 33CytokineEndotheliumCell nucleusReticular cellEpitheliumCell biologyGeneral Biochemistry, Genetics and Molecular BiologyGeneral Agricultural and Biological SciencesGeneral Medicine

摘要: Background Interleukin-33 (IL-33) is an IL-1-like cytokine ligand for the IL-1 receptor-related protein ST2, that activates mast cells and Th2 lymphocytes, and induces production of Th2 …

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