Sensitive and specific multi-cancer detection and localization using methylation signatures in cell-free DNA

作者: Minetta C Liu , GR Oxnard , EA Klein , CSMCC Swanton , MV Seiden

DOI: 10.1016/J.ANNONC.2020.02.011

关键词: StomachBisulfite sequencingAnusCell-free fetal DNAEsophagusInternal medicineGastroenterologyPlasma cell neoplasmConfidence intervalRectumMedicine

摘要: Background Early cancer detection could identify tumors at a time when outcomes are superior and treatment is less morbid. This prospective case-control sub-study (from …

参考文章(25)
B. Vogelstein, N. Papadopoulos, V. E. Velculescu, S. Zhou, L. A. Diaz, K. W. Kinzler, Cancer Genome Landscapes Science. ,vol. 339, pp. 1546- 1558 ,(2013) , 10.1126/SCIENCE.1235122
KC Allen Chan, Peiyong Jiang, Carol WM Chan, Kun Sun, John Wong, Edwin P Hui, Stephen L Chan, Wing Cheong Chan, David SC Hui, Simon SM Ng, Henry LY Chan, Cesar SC Wong, Brigette BY Ma, Anthony TC Chan, Paul BS Lai, Hao Sun, Rossa WK Chiu, YM Dennis Lo, None, Noninvasive detection of cancer-associated genome-wide hypomethylation and copy number aberrations by plasma DNA bisulfite sequencing Proceedings of the National Academy of Sciences of the United States of America. ,vol. 110, pp. 18761- 18768 ,(2013) , 10.1073/PNAS.1313995110
J. M. Croswell, B. S. Kramer, A. R. Kreimer, P. C. Prorok, J.-L. Xu, S. G. Baker, R. Fagerstrom, T. L. Riley, J. D. Clapp, C. D. Berg, J. K. Gohagan, G. L. Andriole, D. Chia, T. R. Church, E. D. Crawford, M. N. Fouad, E. P. Gelmann, L. Lamerato, D. J. Reding, R. E. Schoen, Cumulative incidence of false-positive results in repeated, multimodal cancer screening. Annals of Family Medicine. ,vol. 7, pp. 212- 222 ,(2009) , 10.1370/AFM.942
, Results of Initial Low-Dose Computed Tomographic Screening for Lung Cancer The New England Journal of Medicine. ,vol. 368, pp. 1980- 1991 ,(2013) , 10.1056/NEJMOA1209120
W. J. Kent, C. W. Sugnet, T. S. Furey, K. M. Roskin, T. H. Pringle, A. M. Zahler, a. D. Haussler, The Human Genome Browser at UCSC Genome Research. ,vol. 12, pp. 996- 1006 ,(2002) , 10.1101/GR.229102
R. J. Leary, M. Sausen, I. Kinde, N. Papadopoulos, J. D. Carpten, D. Craig, J. O'Shaughnessy, K. W. Kinzler, G. Parmigiani, B. Vogelstein, L. A. Diaz, V. E. Velculescu, Detection of Chromosomal Alterations in the Circulation of Cancer Patients with Whole-Genome Sequencing Science Translational Medicine. ,vol. 4, ,(2012) , 10.1126/SCITRANSLMED.3004742
US DOE Joint Genome Institute: Hawkins Trevor 4 Branscomb Elbert 4 Predki Paul 4 Richardson Paul 4 Wenning Sarah 4 Slezak Tom 4 Doggett Norman 4 Cheng Jan-Fang 4 Olsen Anne 4 Lucas Susan 4 Elkin Christopher 4 Uberbacher Edward 4 Frazier Marvin 4, RIKEN Genomic Sciences Center: Sakaki Yoshiyuki 9 Fujiyama Asao 9 Hattori Masahira 9 Yada Tetsushi 9 Toyoda Atsushi 9 Itoh Takehiko 9 Kawagoe Chiharu 9 Watanabe Hidemi 9 Totoki Yasushi 9 Taylor Todd 9, Genoscope and CNRS UMR-8030: Weissenbach Jean 10 Heilig Roland 10 Saurin William 10 Artiguenave Francois 10 Brottier Philippe 10 Bruls Thomas 10 Pelletier Eric 10 Robert Catherine 10 Wincker Patrick 10, Department of Genome Analysis, Institute of Molecular Biotechnology: Rosenthal André 12 Platzer Matthias 12 Nyakatura Gerald 12 Taudien Stefan 12 Rump Andreas 12, GTC Sequencing Center: Smith Douglas R. 11 Doucette-Stamm Lynn 11 Rubenfield Marc 11 Weinstock Keith 11 Lee Hong Mei 11 Dubois JoAnn 11, Beijing Genomics Institute/Human Genome Center: Yang Huanming 13 Yu Jun 13 Wang Jian 13 Huang Guyang 14 Gu Jun 15, Multimegabase Sequencing Center, The Institute for Systems Biology: Hood Leroy 16 Rowen Lee 16 Madan Anup 16 Qin Shizen 16, Stanford Genome Technology Center: Davis Ronald W. 17 Federspiel Nancy A. 17 Abola A. Pia 17 Proctor Michael J. 17, University of Oklahoma's Advanced Center for Genome Technology: Roe Bruce A. 22 Chen Feng 22 Pan Huaqin 22, Max Planck Institute for Molecular Genetics: Ramser Juliane 23 Lehrach Hans 23 Reinhardt Richard 23, Cold Spring Harbor Laboratory, Lita Annenberg Hazen Genome Center: McCombie W. Richard 24 de la Bastide Melissa 24 Dedhia Neilay 24, GBF—German Research Centre for Biotechnology: Blöcker Helmut 25 Hornischer Klaus 25 Nordsiek Gabriele 25, Scientific management: National Human Genome Research Institute, US National Institutes of Health: Collins Francis fc23a@ nih. gov 46 b Guyer Mark S. 46 Peterson Jane 46 Felsenfeld Adam 46 Wetterstrand Kris A. 46, Stanford Human Genome Center: Myers Richard M. 18 Schmutz Jeremy 18 Dickson Mark 18 Grimwood Jane 18 Cox David R. 18, University of Washington Genome Center: Olson Maynard V. 19 Kaul Rajinder 19 Raymond Christopher 19, Department of Molecular Biology, Keio University School of Medicine: Shimizu Nobuyoshi 20 Kawasaki Kazuhiko 20 Minoshima Shinsei 20, University of Texas Southwestern Medical Center at Dallas: Evans Glen A. 21 49 50 49 Athanasiou Maria 21 Schultz Roger 21, Office of Science, US Department of Energy: Patrinos Aristides 47, Wellcome Trust: Morgan Michael J. 48, None, Initial sequencing and analysis of the human genome. Nature. ,vol. 409, pp. 860- 921 ,(2001) , 10.1038/35057062
Karen Limmer, MSN, RN, ANP, NP-C, Geri LoBiondo-Wood, PhD, RN, FAAN, Joyce Dains, DrPH, JD, RN, FNP-CB, DPNAP, Predictors of cervical cancer screening adherence in the United States: a systematic review. Journal of the advanced practitioner in oncology. ,vol. 5, pp. 31- 41 ,(2014) , 10.6004/JADPRO.2014.5.1.2
Constance D. Lehman, Robert F. Arao, Brian L. Sprague, Janie M. Lee, Diana S. M. Buist, Karla Kerlikowske, Louise M. Henderson, Tracy Onega, Anna N. A. Tosteson, Garth H. Rauscher, Diana L. Miglioretti, National Performance Benchmarks for Modern Diagnostic Digital Mammography: Update from the Breast Cancer Surveillance Consortium. Radiology. ,vol. 283, pp. 49- 58 ,(2017) , 10.1148/RADIOL.2016161174
Mahul B. Amin, Frederick L. Greene, Stephen B. Edge, Carolyn C. Compton, Jeffrey E. Gershenwald, Robert K. Brookland, Laura Meyer, Donna M. Gress, David R. Byrd, David P. Winchester, The Eighth Edition AJCC Cancer Staging Manual: Continuing to build a bridge from a population‐based to a more “personalized” approach to cancer staging CA: A Cancer Journal for Clinicians. ,vol. 67, pp. 93- 99 ,(2017) , 10.3322/CAAC.21388