Biological Cell Manipulation/Measurement/ Analysis under E-SEM

作者: Toshio Fukuda , Fumihito Arai , Masahiro Nakajima , Toshio Fukuda , Fumihito Arai

DOI: 10.1007/978-3-642-36391-7_8

关键词: Adhesion forceBiological cellEnvironmental scanning electron microscopeElectron microscopeNanotechnologyNanomanipulatorKinematicsAtomic force microscopy cantileverCell stiffnessMaterials science

摘要: In this chapter, the historical development of our Environmental-Scanning Electron Microscope (E-SEM) nanomanipulation system has been presented. The working principles which enable E-SEM to operate under various pressure levels are explained. design nanomanipulator is presented and derivation its kinematics showed confirmed. These two systems, i.e. nanomanipulator, were then integrated for realizing single cells property characterizations.

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