Outcomes of Patients with Renal Cell Carcinoma and Sarcomatoid Dedifferentiation Treated with Nephrectomy and Systemic Therapies: Comparison between the Cytokine and Targeted Therapy Eras

摘要: Purpose: We studied overall survival and prognostic factors in patients with sarcomatoid renal cell carcinoma treated nephrectomy systemic therapy the cytokine targeted eras.Materials Methods: This is a retrospective study of who underwent received at our center era (1987 to 2005) or (2006 2015). Multivariate regression models were used determine association covariables survival.Results: Of 199 167 (83.9%) died (median 16.5 months, 95% CI 15.2–20.9). Survival clear histology was significantly longer vs those nonclear (p = 0.034). Patients synchronous metastatic disease had shorter than metachronous 12.1 23.3 p 0.0064). Biopsy primary tumor m...