The value of endorectal MR imaging to predict positive biopsies in clinically intermediate-risk prostate cancer patients.

作者: J. C. Vilanova , J. Comet , A. Capdevila , J. Barcel� , J. Ll. Dolz

DOI: 10.1007/S003300000616

关键词: RadiologyBiopsyCancerRectal examinationProstate cancerMagnetic resonance imagingMedicineNeuroradiologyInterventional radiologyReceiver operating characteristic

摘要: The aim of this study was to assess the effectiveness endorectal MR imaging in predicting positive biopsy results patients with clinically intermediate risk for prostate cancer. We performed a prospective 81 at detect cancer between January 1997 and December 1998. Intermediate defined as: prostatic specific antigen (PSA) levels 4 10 ng/ml or PSA range 10–20 but negative digital rectal examination (DRE) progressively higher (0.75 year–1). A transrectal sextant after exam, also area suspicion detected by imaging. accuracies were measured, both singly combined level DRE, calculating index receiver operating characteristics (ROC) curve. Cancer 23 (28 %). Overall sensitivity specificity MRI 70 76 %, respectively. Accuracy 71 % estimated from under ROC curve total patient group 84 ng/ml. Positive rate (PBR) 63 imaging, 15 exam. PBR 43 4–10 study, 13 examination. would have avoided biopsies, while missing 30 cancers patients. Endorectal not sufficient predictor biopsies Although we should avoid performing systematic results, as it will miss significant number cancers, selected clinical-biopsy disagreement might benefit

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