Cytokines as a key component of cancer-related inflammation.

作者: Giovanni Germano , Paola Allavena , Alberto Mantovani

DOI: 10.1016/J.CYTO.2008.07.014

关键词: InflammationProinflammatory cytokineAcquired immune systemMacrophage inflammatory proteinChemokineImmunologyCancerTumor necrosis factor alphaMetastasisMedicine

摘要: Inflammatory conditions in some tissues increase the risk of cancer. Cytokines and chemokines are components an intensive dialog promoting angiogenesis, metastasis, subversion adaptive immunity changing response to hormones chemotherapeutic agents. involved cancer-related inflammation represent a target for innovative diagnostic therapeutic strategies, future challenge scientists clinicians.

参考文章(85)
Yuan-Chang Chung, Ya-Fen Chang, Serum interleukin-6 levels reflect the disease status of colorectal cancer. Journal of Surgical Oncology. ,vol. 83, pp. 222- 226 ,(2003) , 10.1002/JSO.10269
Cecilia Garlanda, Federica Riva, Tania Veliz, Nadia Polentarutti, Fabio Pasqualini, Enrico Radaelli, Marina Sironi, Manuela Nebuloni, Elisabetta Omodeo Zorini, Eugenio Scanziani, Alberto Mantovani, Increased Susceptibility to Colitis-Associated Cancer of Mice Lacking TIR8, an Inhibitory Member of the Interleukin-1 Receptor Family Cancer Research. ,vol. 67, pp. 6017- 6021 ,(2007) , 10.1158/0008-5472.CAN-07-0560
Catherine Uyttenhove, Luc Pilotte, Ivan Théate, Vincent Stroobant, Didier Colau, Nicolas Parmentier, Thierry Boon, Benoît J Van den Eynde, None, Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase Nature Medicine. ,vol. 9, pp. 1269- 1274 ,(2003) , 10.1038/NM934
B BIERIE, H MOSES, TGF-β and cancer Cytokine & Growth Factor Reviews. ,vol. 17, pp. 29- 40 ,(2006) , 10.1016/J.CYTOGFR.2005.09.006
Christina M. Annunziata, R. Eric Davis, Yulia Demchenko, William Bellamy, Ana Gabrea, Fenghuang Zhan, Georg Lenz, Ichiro Hanamura, George Wright, Wenming Xiao, Sandeep Dave, Elaine M. Hurt, Bruce Tan, Hong Zhao, Owen Stephens, Madhumita Santra, David R. Williams, Lenny Dang, Bart Barlogie, John D. Shaughnessy, W. Michael Kuehl, Louis M. Staudt, Frequent Engagement of the Classical and Alternative NF-κB Pathways by Diverse Genetic Abnormalities in Multiple Myeloma Cancer Cell. ,vol. 12, pp. 115- 130 ,(2007) , 10.1016/J.CCR.2007.07.004
Douglas M. Noonan, Andrea De Lerma Barbaro, Nicola Vannini, Lorenzo Mortara, Adriana Albini, Inflammation, inflammatory cells and angiogenesis: decisions and indecisions. Cancer and Metastasis Reviews. ,vol. 27, pp. 31- 40 ,(2008) , 10.1007/S10555-007-9108-5
Monica M. Bertagnolli, Craig J. Eagle, Ann G. Zauber, Mark Redston, Scott D. Solomon, KyungMann Kim, Jie Tang, Rebecca B. Rosenstein, Janet Wittes, Donald Corle, Timothy M. Hess, G. Mabel Woloj, Frédéric Boisserie, William F. Anderson, Jaye L. Viner, Donya Bagheri, John Burn, Daniel C. Chung, Thomas Dewar, T. Raymond Foley, Neville Hoffman, Finlay Macrae, Ronald E. Pruitt, John R. Saltzman, Bruce Salzberg, Thomas Sylwestrowicz, Gary B. Gordon, Ernest T. Hawk, Celecoxib for the Prevention of Sporadic Colorectal Adenomas The New England Journal of Medicine. ,vol. 355, pp. 873- 884 ,(2006) , 10.1056/NEJMOA061355
John L. Langowski, Xueqing Zhang, Lingling Wu, Jeanine D. Mattson, Taiying Chen, Kathy Smith, Beth Basham, Terrill McClanahan, Robert A. Kastelein, Martin Oft, IL-23 promotes tumour incidence and growth Nature. ,vol. 442, pp. 461- 465 ,(2006) , 10.1038/NATURE04808
Alexander Khoruts, Laura Stahnke, Craig J. McClain, George Logan, John I. Allen, Circulating tumor necrosis factor, interleukin-1 and interleukin-6 concentrations in chronic alcoholic patients Hepatology. ,vol. 13, pp. 267- 276 ,(1991) , 10.1002/HEP.1840130211
Fran Balkwill, Cancer and the chemokine network Nature Reviews Cancer. ,vol. 4, pp. 540- 550 ,(2004) , 10.1038/NRC1388