作者: Michela Bruschi , Doris Steinmüller-Nethl , Walter Goriwoda , Michael Rasse
DOI: 10.1155/2015/527426
关键词: Biomedical engineering 、 Osseointegration 、 Dental implant 、 Titanium 、 Wetting 、 Surface modification 、 Surface energy 、 Materials science 、 Zirconium 、 Implant
摘要: Since Branemark discovered the favorable effects of titanium in bone healing 1965, has emerged as gold standard bulk material for present-time dental implantology. In course years researchers aimed improvement implants performance even at compromised implant sites and multiple factors were investigated influencing osseointegration. This review summarizes clarifies four that are currently recognized being relevant to influence tissue-implant contact ratio: materials coatings, topography, surface energy, biofunctionalization. The macrodesigns (e.g., titanium, zirconium, stainless steel, tantalum, magnesium) provide mechanical stability their on cells can be additionally improved by treatment with various (calcium phosphates, strontium, bioglasses, diamond-like carbon, diamond). Surface topography modified via different techniques increase bone-implant contact, example, plasma-spraying, grit-blasting, acid-etching, microarc oxidation. energy wettability polarity) showed a strong effect cell behavior adhesion. Functionalization bioactive molecules (via physisorption, covalent binding, or carrier systems) targets enhanced Despite satisfying clinical results presently used materials, further research innovative surfaces is inevitable pursuit perfection soft hard tissue performance.