Metastasis Associated Lung Adenocarcinoma Transcript 1: An update on expression pattern and functions in carcinogenesis
作者： Soudeh Ghafouri-Fard , Asghar Ashrafi Hafez , Mohammad Taheri
DOI: 10.1016/J.YEXMP.2019.104330
关键词: Cancer research 、 Breast cancer 、 Colorectal cancer 、 Adenocarcinoma 、 MALAT1 、 Metastasis 、 Biology 、 Cancer 、 Lung cancer 、 Carcinogenesis
摘要: The Metastasis Associated Lung Adenocarcinoma Transcript 1 (MALAT1) is among long non-coding RNAs (lncRNAs) which has disapproved the old term of "junk DNA" was used for majority human genome are not transcribed to proteins. An extensive portion literature points fundamental role this lncRNA in tumorigenesis process diverse cancers ranging from solid tumors leukemia. Being firstly identified lung cancer, it prognostic and diagnostic values several cancer types. Consistent with proposed oncogenic roles lncRNA, most studies have shown up-regulation MALAT1 malignant tissues compared non-malignant/normal same source. However, few down-regulation breast endometrial colorectal glioma. In current study, we conducted a comprehensive search provided an up-date on biology. Our investigation underscores potential as diagnostic/prognostic marker putative therapeutic target MALAT1.
sbmu.ac.ir参考文章(255)
Yingjun Li, Chengzhen Bao, Simeng Gu, Ding Ye, Fangyuan Jing, Chunhong Fan, Mingjuan Jin, Kun Chen, Associations between novel genetic variants in the promoter region of MALAT1 and risk of colorectal cancer Oncotarget. ,vol. 8, pp. 92604- 92614 ,(2017) , 10.18632/ONCOTARGET.21507
Wei Chen, Wei Zhao, Li Zhang, Lixin Wang, Jipeng Wang, Zongren Wan, Yongqing Hong, Liang Yu, MALAT1-miR-101-SOX9 feedback loop modulates the chemo-resistance of lung cancer cell to DDP via Wnt signaling pathway. Oncotarget. ,vol. 8, pp. 94317- 94329 ,(2017) , 10.18632/ONCOTARGET.21693
Ke‐Ke Sun, Ping‐Ping Hu, Feng Xu, Prognostic significance of long non-coding RNA MALAT1 for predicting the recurrence and metastasis of gallbladder cancer and its effect on cell proliferation, migration, invasion, and apoptosis. Journal of Cellular Biochemistry. ,vol. 119, pp. 3099- 3110 ,(2018) , 10.1002/JCB.26451
Ying-Hsia Chu, Heather Hardin, David F. Schneider, Herbert Chen, Ricardo V. Lloyd, MicroRNA-21 and long non-coding RNA MALAT1 are overexpressed markers in medullary thyroid carcinoma. Experimental and Molecular Pathology. ,vol. 103, pp. 229- 236 ,(2017) , 10.1016/J.YEXMP.2017.10.002
Haibiao Xie, Xinhui Liao, Zhicong Chen, Yuan Fang, Anbang He, Yucheng Zhong, Qunjun Gao, Huizhong Xiao, Jianfa Li, Weiren Huang, Yuchen Liu, LncRNA MALAT1 Inhibits Apoptosis and Promotes Invasion by Antagonizing miR-125b in Bladder Cancer Cells. Journal of Cancer. ,vol. 8, pp. 3803- 3811 ,(2017) , 10.7150/JCA.21228
Jun Huang, Yuting Yang, Fang Fang, Ke Liu, MALAT1 modulates the autophagy of retinoblastoma cell through miR-124-mediated stx17 regulation. Journal of Cellular Biochemistry. ,vol. 119, pp. 3853- 3863 ,(2018) , 10.1002/JCB.26464
Yuzhou Wang, Yijin Zhou, Zhicheng Yang, Baoying Chen, Wennan Huang, Yongyuan Liu, Ying Zhang, MiR-204/ZEB2 axis functions as key mediator for MALAT1-induced epithelial-mesenchymal transition in breast cancer. Tumor Biology. ,vol. 39, pp. 1010428317690998- ,(2017) , 10.1177/1010428317690998
Dazun Shi, Yu Zhang, Rong Lu, Yi Zhang, The long non-coding RNA MALAT1 interacted with miR-218 modulates choriocarcinoma growth by targeting Fbxw8. Biomedicine & Pharmacotherapy. ,vol. 97, pp. 543- 550 ,(2018) , 10.1016/J.BIOPHA.2017.10.083
Zhi-Chang Zhang, Chun Tang, Yang Dong, Jing Zhang, Ting Yuan, Shi-Cong Tao, Xiao-Lin Li, Targeting the long noncoding RNA MALAT1 blocks the pro-angiogenic effects of osteosarcoma and suppresses tumour growth. International Journal of Biological Sciences. ,vol. 13, pp. 1398- 1408 ,(2017) , 10.7150/IJBS.22249
Haidy E. Zidan, Rehab A. Karam, Omnia S. El-Seifi, Tamer M. Abd Elrahman, Circulating long non-coding RNA MALAT1 expression as molecular biomarker in Egyptian patients with breast cancer Cancer Genetics. ,vol. 220, pp. 32- 37 ,(2018) , 10.1016/J.CANCERGEN.2017.11.005