作者: Suzanne L Topalian , Charles G Drake , Drew M Pardoll
DOI: 10.1016/J.COI.2011.12.009
关键词: Antigen 、 PD-L1 、 Immunology 、 Immunity 、 Immune checkpoint 、 Cancer immunotherapy 、 Tumor microenvironment 、 T cell 、 Biology 、 Immune system
摘要: … using blocking … PD-1: PD-L1 interactions appear to promote the induction/conversion and maintenance of Tregs, suggesting an additional mechanism for immunosuppression in a tumor …