Comparative genomics of two invasive mosquitoes (Aedes aegypti and Aedes albopictus) from the Indo-Pacific

摘要: The arbovirus vectors Aedes aegypti (yellow fever mosquito) and Ae. albopictus (Asian tiger are both common throughout the Indo-Pacific region, where 70% of global dengue transmission occurs. For all populations invasive, having spread from an initial native range Africa, while for includes invasive those range: putatively, India to Japan Southeast Asia. This study analyses population genomics 480 these mosquitoes sampled 27 locations in Indo-Pacific. We compared patterns genetic differentiation investigate pathways invasion ongoing gene flow species, infer potential native-range boundaries cryptic subspecies albopictus. also tested landscape genomic hypotheses that would increase with geographical distance be lower between high connectivity human transportation routes, primary means dispersal at scales. found distances were generally higher aegypti, Pacific most highly differentiated. differentiated Vanuatu, Indonesia Sri Lanka; latter two may represent ancestral or subspecies, respectively. Genetic increased distance, they decreased routes. Contrary situation we evidence long-distance colonisation events, including Mauritius East Asia Fiji Our direct comparisons indicate likely differences ecology despite their phylogenetic proximity, broadly sympatric distributions similar use transport disperse. findings will assist biosecurity operations trace source material biocontrol benefit matching backgrounds released local populations.