Efficacy of an alcohol-free chlorhexidine mouthrinse as an antimicrobial agent☆☆☆★★★♢♢♢

摘要: Abstract Statement of problem. Antimicrobial mouthrinses have become an important part comprehensive dental care. However, that contain alcohol been shown to be detrimental patients undergoing radiation therapy for head and neck cancer, some immunocompromised patients, families with small children, persons sensitive alcohol. Purpose. This study evaluated the effectiveness alcohol-free, 0.12% chlorhexidine mouthrinse in reducing microbial levels when compared commercially available (CHX) essential oils mouthrinses. Material methods. consisted both vitro vivo investigations. The double-blind included 32 subjects randomly assigned 3 groups, equalized according indices tested. One group (n = 11) received rinse; second CHX; last 10) alcohol-free CHX. Subjects were asked not use any mechanical means oral hygiene 21 days. Streptococcus mutans strip tests. Results. Mean plaque scores CHX products decreased after days, whereas mean increased. Bleeding gingival index all groups increased, which may due initially healthy tissues participants. Relative growth S 0 counts remained varied.(J Prosthet Dent 1998;80:685-90.)