Role of inflammation and its treatment in ESRD patients

摘要: As renal function declines, the prevalence of both malnutrition and cardiovascular disease increase. Both vascular correlate with levels markers inflammation in patients treated dialysis those not yet on dialysis. While it is possible that (increased C-reactive protein (CRP) or interleukin-6 (IL-6)) are a result arising from atherosclerotic process, changes endothelial cell gene expression, plasma composition lipoprotein structure arise likely to be atherogenic. The causes multifactorial. CRP associated risk general population decrease following treatment HMG-CoA reductase inhibitors. It speculated use these agents directly suppressing may have treating inflammatory-malnutrition syndrome patients.