Review paper: Cancer chemopreventive compounds and canine cancer.

摘要: Canine cancer has become more prevalent in recent years because of increased life expectancy and greater attention to the health pets. The range cancers seen dogs is as diverse that human patients, despite intensive therapeutic interventions, fatality rates remain unacceptably high both species. Chemoprevention therefore an important means confronting this disease. Because domestic pets share our environment, cross-application study protumorigenic antitumorigenic factors shared environment will benefit all species, leading development new families less toxic compounds based on novel established molecular targets. Currently, most interesting preventive agents are nonsteroidal anti-inflammatory drugs, peroxisome proliferator-activated receptor-gamma ligands, dietary compounds. This article provides overview what known about how these affect signaling neoplastic disease, with reference reported application and/or where available.