Separation and Migration Behavior of Dichlorophenols in β‐Cyclodextrin‐Modified Capillary Zone Electrophoresis

作者: Chih-Yu Chen , Yu-Chih Liu , I-Chin Chien , Chung-Chuan Hsueh , Chen-Hsing Lin

DOI: 10.1002/JCCS.201400085

关键词: CyclodextrinChromatographyChemistryCapillary electrophoresisElectrolyteDCPSβ cyclodextrins

摘要: The separation and migration behavior of six isomeric dichlorophenols (DCPs) in cyclodextrin-modified capillary zone electrophoresis (CD-CZE) using a phosphate-borate buffer at alkaline pH with β-CD hydroxypropyl-β-CD (HP-β-CD) as electrolyte modifiers were investigated. influence the concentration β-cyclodextrins examined. results indicate that baseline DCPs can be achieved addition range 2.0-10 mM or HP-β-CD 4.0-10 10.0. Binding constants to β-CDs evaluated for better understanding interaction β-CDs.

参考文章(28)
Koji Otsuka, Shigeru Terabe, Teiichi Ando, Electrokinetic chromatography with micellar solutions Journal of Chromatography A. ,vol. 348, pp. 39- 47 ,(1985) , 10.1016/S0021-9673(01)92438-0
Stephen A.C. Wren, Raymond C. Rowe, Theoretical aspects of chiral separation in capillary electrophoresis Journal of Chromatography A. ,vol. 603, pp. 235- 241 ,(1992) , 10.1016/0021-9673(92)85366-2
Ketevan Lomsadze, Elena Domínguez Vega, Antonio Salgado, Antonio L. Crego, Gerhard K.E. Scriba, Maria Luisa Marina, Bezhan Chankvetadze, Separation of enantiomers of norephedrine by capillary electrophoresis using cyclodextrins as chiral selectors: comparative CE and NMR studies. Electrophoresis. ,vol. 33, pp. 1637- 1647 ,(2012) , 10.1002/ELPS.201200062
Ching-Erh Lin, Wei-Ssu Liao, Kuo-Hsing Chen, Enantioseparation of phenothiazines in cyclodextrin-modified capillary zone electrophoresis: reversal of migration order. Electrophoresis. ,vol. 24, pp. 3139- 3146 ,(2003) , 10.1002/ELPS.200305558
Hiroyuki Nishi, Shigeru Terabe, Optical resolution of drugs by capillary electrophoretic techniques Journal of Chromatography A. ,vol. 694, pp. 245- 276 ,(1995) , 10.1016/0021-9673(94)00682-Y
Petr Praus, Václav Dombek, Separation of chlorophenols by capillary isotachophoresis Analytica Chimica Acta. ,vol. 277, pp. 97- 101 ,(1993) , 10.1016/0003-2670(93)85094-Z
Ching-Erh Lin, Chung-Chuan Hsueh, Wei-Chen Lin, Chia-Chieh Chang, Migration behavior and separation of trichlorophenols by capillary zone electrophoresis Journal of Chromatography A. ,vol. 746, pp. 295- 299 ,(1996) , 10.1016/0021-9673(96)00394-9