Retroviral protease inhibiting compounds.

作者: Daniel W. Norbeck , Chen Zhao , Dale J. Kempf , Hing Leung Sham

DOI:

关键词: Retroviral proteaseVirologyChemistryHuman immunodeficiency virus (HIV)

摘要: A retroviral protease inhibiting compound of the formula A--X--B is disclosed. Also disclosed are a composition and method for treating an HIV infection. processes intermediates useful preparation inhibitors.

参考文章(102)
Lucien Marchal, Ludovic Rodriguez, Lactam-n-acetic acids and their amides ,(1979)
Shinichiro Miyaoka, Shinobu Hayashi, Teruji Sekozawa, Motohisa Funabashi, Method and apparatus for controlling pressure and flow in water distribution networks ,(1983)
Eugene Zeffren, Philip L. Hall, The study of enzyme mechanisms ,(1973)
Bruce David Korant, Charles Adrian Kettner, Method for preparing specific inhibitors of virus-specified proteases ,(1984)
Brian Walter Metcalf, Geoffrey Bainbridge Dreyer, William Francis Huffman, Thomas Downing Meek, Michael Lee Moore, Retroviral protease binding peptides ,(1989)
Akira Hosomi, Koichiro Ogata, Koichiro Hoashi, Shinya Kohra, Yoshinori Tominaga, NOVEL, ARYLTHIOMETHYLATION OF CARBONYL COMPOUNDS USING ARYLTHIOMETHYLTRIMETHYLSILANES CATALYZED BY FLUORIDE IONS. NEW ROUTE TO β-HYDROXYARYLSULFIDES Chemical & Pharmaceutical Bulletin. ,vol. 36, pp. 3736- 3738 ,(1988) , 10.1248/CPB.36.3736
Daniel W. Norbeck, John M. Leonard, Dale J. Kempf, Richard J. Bertz, Method for improving pharmacokinetics ,(1996)
Laman A. Al-Razzak, Kennan C. Marsh, Dilip Kaul, Lourdes P. Manning, Pharmaceutical compositions containing hiv protease inhibitors ,(1995)
Paul Evans, Paul Ravenscroft, Tony Gordon Roberts, Crystalline oxathiolane derivatives ,(1992)
Wolfgang O. Reder, Georg Schneider, Doctor blade bar assembly ,(1993)