Pathophysiology and Management of Variceal Bleeding.

摘要: Cirrhosis is the fifth leading cause of death in adults. Advanced cirrhosis can significant portal hypertension (PH), which responsible for many complications observed patients with cirrhosis, such as varices. If pressure exceeds a certain threshold, patient at risk developing life-threatening bleeding from Variceal has high incidence among liver and carries mortality morbidity. The management variceal complex, often requiring multidisciplinary approach involving pharmacological, endoscopic, radiologic interventions. In terms management, three stages be considered: primary prophylaxis, active bleeding, secondary prophylaxis. main goal prophylaxis to prevent bleeding. However, medical emergency that requires swift intervention stop achieve durable hemostasis. We describe pathophysiology PH contextualize formation gastric esophageal also discuss currently available treatments compare how they fare each stage clinical special focus on drugs or assist achieving