Effect of macroscale formation of intraluminal thrombus on blood flow in abdominal aortic aneurysms.

摘要: A mathematical approach of blood flow within an abdominal aortic aneurysm (AAA) with intraluminal thrombus (ILT) is presented. The macroscale formation ILT modeled as a growing porous medium variable porosity and permeability according to values proposed in the literature. model outlines effect on AAAs. numerical solution obtained by employing structured computational mesh idealized fusiform AAA geometry applying Galerkin weighted residual method generalized curvilinear coordinates. Results velocity pressure fields independent cases without are presented discussed. vortices that develop aneurysmal cavity studied visualized becomes more condensed. From mechanistic point view, reduction bulge pressure, thickening, supports observation could protect from possible rupture. also predicts relocation maximum region toward zone proximal neck aneurysm. However, other mechanisms, such gradual wall weakening usually accompany formation, which not included this study, may offset effect.