Asbestiform Amphiboles and Cleavage Fragments Analogues: Overview of Critical Dimensions, Aspect Ratios, Exposure and Health Effects

作者: Laura Gaggero , Sebastiano La Maestra , Gaia M. Militello

DOI: 10.3390/MIN11050525

关键词: TremoliteAsbestiformEnvironmental chemistryActinoliteAsbestosChrysotileEnvironmental exposureAmphiboleAnthophylliteChemistry

摘要: The term asbestos refers to a group of serpentine (chrysotile) and amphibole (amosite, crocidolite, anthophyllite, tremolite actinolite) minerals with fibrous habit. Their chemical-physical properties make them one the most important inorganic materials for industrial purposes technological applications. However, extraction, use marketing these have been prohibited due proven harmful effects, mainly involving respiratory system. In addition known six classified as asbestos, natural amphiboles polymorphs antigorite lizardite, despite having same composition do not morphology. These develop chemical geometric (length > 5 μm, width 3:1), but morphological, analogies which is regulated by WHO. debate about their potential hazardous open ongoing; therefore, morphological characterization has key role in establishing reliable hazard scenario. This review focuses on evaluating relevant papers, evidencing need reappraisal. Different vitro, vivo epidemiological studies report information cleavage fragments critical dimensions similar fibres, very few works target below µm length. Breathable smaller fibres could deleterious effects human health cannot be disregarded from risk assessment process. Furthermore, suggest that carcinogenic nature short excluded. highlights it worth investigating this size range elongated mineral particles fibres.

参考文章(56)
Yuwadee Ngamwong, Wimonchat Tangamornsuksan, Ornrat Lohitnavy, Nathorn Chaiyakunapruk, C. Norman Scholfield, Brad Reisfeld, Manupat Lohitnavy, Additive Synergism between Asbestos and Smoking in Lung Cancer Risk: A Systematic Review and Meta-Analysis PLOS ONE. ,vol. 10, pp. e0135798- 19 ,(2015) , 10.1371/JOURNAL.PONE.0135798
D.R. Van Orden, K.A. Allison, R.J. Lee, Differentiating Amphibole Asbestos from Non-Asbestos in a Complex Mineral Environment: Indoor and Built Environment. ,vol. 17, pp. 58- 68 ,(2008) , 10.1177/1420326X07087006
John Addison, Ernest E. McConnell, A review of carcinogenicity studies of asbestos and non-asbestos tremolite and other amphiboles Regulatory Toxicology and Pharmacology. ,vol. 52, pp. S187- S199 ,(2008) , 10.1016/J.YRTPH.2007.10.001
Jooyeon Hwang, Gurumurthy Ramachandran, Peter C. Raynor, Bruce H. Alexander, Jeffrey H. Mandel, The Relationship Between Various Exposure Metrics for Elongate Mineral Particles (EMP) in the Taconite Mining and Processing Industry Journal of Occupational and Environmental Hygiene. ,vol. 11, pp. 613- 624 ,(2014) , 10.1080/15459624.2014.890287
JOHN M. G. DAVIS, JOHN ADDISON, CAROL McINTOSH, BRIAN G. MILLER, KAREN NIVEN, Variations in the Carcinogenicity of Tremolite Dust Samples of Differing Morphology Annals of the New York Academy of Sciences. ,vol. 643, pp. 473- 490 ,(1991) , 10.1111/J.1749-6632.1991.TB24497.X
F. Pott, F. Huth, K. H. Friedrichs, Tumorigenic effect of fibrous dusts in experimental animals. Environmental Health Perspectives. ,vol. 9, pp. 313- 315 ,(1974) , 10.1289/EHP.749313
Ann G. Wylie, H.Catherine W. Skinner, Joanne Marsh, Howard Snyder, Carmala Garzione, Damian Hodkinson, Roberta Winters, Brooke T. Mossman, Mineralogical Features Associated with Cytotoxic and Proliferative Effects of Fibrous Talc and Asbestos on Rodent Tracheal Epithelial and Pleural Mesothelial Cells Toxicology and Applied Pharmacology. ,vol. 147, pp. 143- 150 ,(1997) , 10.1006/TAAP.1997.8276
Chiara Riganti, Elisabetta Aldieri, Loredana Bergandi, Maura Tomatis, Ivana Fenoglio, Costanzo Costamagna, Bice Fubini, Amalia Bosia, Dario Ghigo, Long and short fiber amosite asbestos alters at a different extent the redox metabolism in human lung epithelial cells Toxicology and Applied Pharmacology. ,vol. 193, pp. 106- 115 ,(2003) , 10.1016/S0041-008X(03)00339-9