Advanced age a risk factor for illness temporally associated with yellow fever vaccination.

摘要: In 1998, the Centers for Disease Control and Prevention was notified of severe illnesses one death, temporally associated with yellow fever (YF) vaccination, in two elderly U.S. residents. Because cases were unusual adverse events following YF vaccination had not been studied, we estimated age-related reporting rates systemic illness vaccination. We found that rate reported among vaccinees higher than 25 to 44 years age. also additional deaths vaccinees. These data signal a potential problem but are sufficient reliably estimate incidence or understand underlying mechanisms; therefore, enhanced surveillance is needed. remains an important cause travel disease-endemic regions increasing. For travelers, risk death due infection should be balanced against vaccine.