Retrospective evaluation of a computerized physician order entry adaptation to prevent prescribing errors in a pediatric emergency department.

作者: Brian E. Sard , Kathleen E. Walsh , Gheorghe Doros , Megan Hannon , Wayne Moschetti

DOI: 10.1542/PEDS.2007-3064

关键词: Decision support systemIntensive care medicineEmergency departmentMedical prescriptionDosingClinical decision support systemMedicineComputerized physician order entryHealth careRetrospective cohort study

摘要: Medication errors are a constant challenge for providers and have potentially serious consequences patients. Pediatric populations at unique significant risks with respect to medical errors.1 The use of weight-based dosing, off-label drug usage, limited reserves withstand dosing errors, inability communicate health care personnel prevent an error or signal that one has occurred contributing factors.2,3 Children pharmacokinetic pharmacodynamic differences, compared adults, which make them more susceptible medication errors. Small calculation may translate into large complications, such as decimal causing 10-fold dose increase.4 emergency department (ED) environment presents additional risk because the nature provided, high patient volume, stress, noise, time pressures, unfamiliar patients.1 Therefore, pediatric ED is particularly It estimated prescribing occur in 10% visits ED.5 To date, no studies exist regarding impact computerized physician order entry (CPOE) on ED. Most adverse reactions prescribing.6,7 In inpatient setting, 74% 79% stage ordering, most frequent type was error.6,7 CPOE been shown reduce rates hospitalized children.8,9 However, recent little effect some systems preventing populations, new, computer-related sometimes emerge.10 Despite these shortcomings, supported by Institute Medicine, Leapfrog Group, Safe Practices, American Medical Association, Academy Pediatrics, others safety practice implement.11–18 CPOE used conjunction decision support adults.13,14,19 Examples include suggested regimens age-specific doses, drug-drug interaction warnings, allergy warnings. A system targeted (eg, creatinine clearance renal antibiotics) be effective adult patients insufficiency.20 study involving 1933 children from 3 maintenance organizations, electronic prescription ordering without did not lower potential outpatient prescriptions,21 suggests necessary children. pediatrics-specific clinical way harmful inpatients.7 In effort we designed quicklist provides supplying pediatric, doses formulary-approved drugs commonly prescribed medications our ED. purpose this determine whether addition reduced rate

参考文章(22)
Erin R Stucky, Prevention of medication errors in the pediatric inpatient setting. Pediatrics. ,vol. 112, pp. 431- 436 ,(2003) , 10.1542/PEDS.112.2.431
Eran Kozer, Dennis Scolnik, Tara Keays, Kevin Shi, Tracy Luk, Gideon Koren, Large errors in the dosing of medications for children. The New England Journal of Medicine. ,vol. 346, pp. 1175- 1176 ,(2002) , 10.1056/NEJM200204113461518
Lucian L Leape, David W Bates, David J Cullen, Jeffrey Cooper, Harold J Demonaco, Theresa Gallivan, Robert Hallisey, Jeanette Ives, Nan Laird, Glenn Laffel, Roberta Nemeskal, Laura A Petersen, Kathy Porter, Deborah Servi, Brian F Shea, Stephen D Small, Bobbie J Sweitzer, B Taylor Thompson, Martha Vander Vliet, David Bates, Patricia Hojnowski-Diaz, Stephen Petrycki, Michael Cotugno, Heather Patterson, Mairead Hickey, Sharon Kleefield, Ellen Kinneally, Margaret Dempsey Clapp, J Richard Hackman, Amy Edmondson, Systems Analysis of Adverse Drug Events JAMA. ,vol. 274, pp. 35- 43 ,(1995) , 10.1001/JAMA.1995.03530010049034
Heather A. McPhillips, Christopher J. Stille, David Smith, Julia Hecht, John Pearson, John Stull, Kristin DeBellis, Susan Andrade, Marlene Miller, Rainu Kaushal, Jerry Gurwitz, Robert L. Davis, Potential Medication Dosing Errors in Outpatient Pediatrics The Journal of Pediatrics. ,vol. 147, pp. 761- 767 ,(2005) , 10.1016/J.JPEDS.2005.07.043
A. L. Potts, F. E. Barr, D. F. Gregory, L. Wright, N. R. Patel, Computerized Physician Order Entry and Medication Errors in a Pediatric Critical Care Unit Pediatrics. ,vol. 113, pp. 59- 63 ,(2004) , 10.1542/PEDS.113.1.59
K. E. Walsh, W. G. Adams, H. Bauchner, R. J. Vinci, J. B. Chessare, M. R. Cooper, P. M. Hebert, E. G. Schainker, C. P. Landrigan, Medication errors related to computerized order entry for children. Pediatrics. ,vol. 118, pp. 1872- 1879 ,(2006) , 10.1542/PEDS.2006-0810
Bea Gollihare, Thomas A. Wunderlich, James R. Guidry, Alan I. Leibowitz, John C. Peirce, Lee Lemelson, Mark A. Heisler, Cynthia Susong, Robert A. Raschke, A Computer Alert System to Prevent Injury From Adverse Drug Events: Development and Evaluation in a Community Teaching Hospital JAMA. ,vol. 280, pp. 1317- 1320 ,(1998) , 10.1001/JAMA.280.15.1317
Conrad V Fernandez, Jane Gillis-Ring, Strategies for the prevention of medical error in pediatrics. The Journal of Pediatrics. ,vol. 143, pp. 155- 162 ,(2003) , 10.1067/S0022-3476(03)00244-0
L. L. Leape, Systems analysis of adverse drug events. ADE Prevention Study Group JAMA: The Journal of the American Medical Association. ,vol. 274, pp. 35- 43 ,(1995) , 10.1001/JAMA.274.1.35
Robert S Gerstle, Christoph U Lehmann, Council on Clinical Information Technology, None, Electronic prescribing systems in pediatrics: the rationale and functionality requirements. Pediatrics. ,vol. 119, pp. 1229- 1231 ,(2007) , 10.1542/PEDS.2007-0889