Lung transplantation in patients 70 years old or older: Have outcomes changed after implementation of the lung allocation score?

摘要: Objective The objective of the present study was to evaluate whether outcomes lung transplantation in patients aged 70 years or older have changed after implementation allocation score May 2005. Methods Patients undergoing primary from 1995 2009 were identified United Network for Organ Sharing registry. stratification pre-lung era versus era. Risk-adjusted multivariate Cox regression and Kaplan-Meier analyses conducted effect age on 1-year post-transplant mortality compared with a reference cohort 60 69 years. Results Of overall 15,726 adult period, 225 (1.4%) old 4634 (29.5%) old. larger before (3.1% vs 0.3%, P  = .02) but not (hazard ratio, 1.02; 95% confidence interval, 0.71-1.46;  = .92). Similarly, survival significantly reduced (56.7% 76.3%,  = .006) (79.0% 80.0%,  = .72). Conclusions Recipients proportion score. Although associated increased post-lung era, is currently comparable those Therefore, should serve as an absolute contraindication