Effects of stevia, aspartame, and sucrose on food intake, satiety, and postprandial glucose and insulin levels
作者： Stephen D Anton , Corby K Martin , Hongmei Han , Sandra Coulon , William T Cefalu
DOI: 10.1016/J.APPET.2010.03.009
关键词: Blood sugar 、 Taste 、 Insulin 、 Aspartame 、 Weight management 、 Postprandial 、 Meal 、 Food science 、 Calorie
摘要: Consumption of sugar-sweetened beverages may be one the dietary causes metabolic disorders, such as obesity. Therefore, substituting sugar with low-calorie sweeteners an efficacious weight management strategy. We tested effect preloads containing stevia, aspartame, or sucrose on food intake, satiety, and postprandial glucose insulin levels. Design: 19 healthy lean (BMI = 20.0 – 24.9) 12 obese 30.0 39.9) individuals 18 to 50 years old completed three separate test days during which they received stevia (290 kcal), aspartame (493 kcal) before lunch dinner meal. The preload order was balanced, intake (kcal) directly calculated. Hunger satiety levels were reported after meals, every hour throughout afternoon. Participants provided blood samples immediately 20 minutes preload. Despite caloric difference in vs. 493 kcals), participants did not compensate by eating more at their meals when consumed versus (mean differences over entire day between 301 kcal, p < .01; 330 .01). Selfreported hunger differ condition. Stevia significantly lowered compared (p .01), both .05). When consuming preloads, either meal similar higher calorie
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