Synthesis of sterols and proteins in liver biopsies from obese patients subjected to gastric or jejunoileal bypass operations.
作者： S. A. Evensen , S. Ritland , K. Nygaard , E. Nilsen , S. Skrede
DOI: 10.3109/00365528109182027
关键词: Control subjects 、 Morbidly obese 、 Liver disease 、 Obesity 、 Jejunoileal bypass 、 Weight loss 、 Gastroenterology 、 Gastric bypass 、 Internal medicine 、 Endocrinology 、 Liver biopsy 、 Medicine
摘要: Incorporation of 14C-acetate into digitonin-precipitable sterols and 3H-leucine proteins was examined in per- or post-operative liver biopsies from morbidly obese patients subjected to either gastric jejunoileal bypass operations. Biopsies obtained non-obese without disease served as controls. precursors peroperative (mean weight, 131 kg) did not differ that control subjects 64 kg). However, eight 11–53 months after weight loss, 32% initial weight) showed an eightfold increased 14C incorporation sterols, whereas the group. The results postoperative (3–12 months) 9 25% significantly those 15 markedly stimulated bi...
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