Regio- and Enantioselective Formal Hydroamination of Enamines for the Synthesis of 1,2-Diamines
作者： Lu Yu , Peter Somfai
关键词: Combinatorial chemistry 、 Enamine 、 Catalysis 、 Enantioselective synthesis 、 Amine gas treating 、 Hydroamination 、 Molecule 、 Chemistry
摘要: The asymmetric formal hydroamination of enamines using a CuH catalyst is reported. method provides straightforward and efficient approach to the synthesis chiral 1,2-dialkyl amines in good yields with high levels enantioselectivities for broad range substrates, should have significant value preparation molecules bearing 1,2-diamine motif.
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