Continued influence of preoperative renal function on outcome of orthotopic liver transplant (OLTX) in the US: where will MELD lead us?

摘要: Renal function is a component of the Model for End Stage Liver Disease (MELD), We queried 1999-2004 OPTN/UNOS database to determine whether preoperative renal remained an important determinant survival in primary deceased donor liver transplant alone patients (DDLTA) or combined kidney (KLTX). examined creatinine, replacement therapy (RRT), incidence KLTX, and patient 34 months before after introduction MELD performed multivariate Cox regression analysis time death. Preoperative independent predictor DDLTA but not KLTX. When compared with serum creatinine 0-0.99 mg/dL, from 1-1.99 >2.0 those requiring RRT, receiving KLTX had relative risk death following 1.11, 1.58, 1.77, 1.44 respectively. RRT better than RRT. Since MELD, number have increased. Despite this, orthotopic (OLTX) different prior MELD.