Persistent effects of maternal deprivation on HPA regulation can be reversed by feeding and stroking, but not by dexamethasone.

作者: Van Oers , De Kloet , Levine

DOI: 10.1046/J.1365-2826.1999.00329.X

关键词: Glucocorticoid receptorHippocampus (mythology)Basal (phylogenetics)CorticosteroneDexamethasoneMaternal deprivationEndocrinologyHypothalamusInternal medicineMedicineMineralocorticoid

摘要: Maternal deprivation of neonatal rats for 24 h has immediate and persistent effects on hypothalamic‐pituitary‐adrenal (HPA) regulation. Immediately after deprivation …

参考文章(32)
Helga J.J. van Oers, E. Ronald de Kloet, Tara Whelan, Seymour Levine, Maternal Deprivation Effect on the Infant’s Neural Stress Markers Is Reversed by Tactile Stimulation and Feeding But Not by Suppressing Corticosterone The Journal of Neuroscience. ,vol. 18, pp. 10171- 10179 ,(1998) , 10.1523/JNEUROSCI.18-23-10171.1998
Michael J. Meaney, David H. Aitken, Victor Viau, Shakti Sharma, Alain Sarrieau, Neonatal handling alters adrenocortical negative feedback sensitivity and hippocampal type II glucocorticoid receptor binding in the rat. Neuroendocrinology. ,vol. 50, pp. 597- 604 ,(1989) , 10.1159/000125287
Helga J. J. van Oers, E. Ronald de Kloet, Seymour Levine, Persistent, but Paradoxical, Effects on HPA Regulation of Infants Maternally Deprived at Different Ages Stress. ,vol. 1, pp. 249- 261 ,(1997) , 10.3109/10253899709013745
Seymour Levine, David M. Huchton, Sandra G. Wiener, Patricia Rosenfeld, Time course of the effect of maternal deprivation on the hypothalamic-pituitary-adrenal axis in the infant rat Developmental Psychobiology. ,vol. 24, pp. 547- 558 ,(1991) , 10.1002/DEV.420240803
Mark A. Smith, Su-Yong Kim, Helga J. J. van Oers, Seymour Levine, Maternal Deprivation and Stress Induce Immediate Early Genes in the Infant Rat Brain Endocrinology. ,vol. 138, pp. 4622- 4628 ,(1997) , 10.1210/ENDO.138.11.5529
A. Nicot, W. Rostène, A. Bérod, Differential expression of neurotensin receptor mRNA in the dopaminergic cell groups of the rat diencephalon and mesencephalon Journal of Neuroscience Research. ,vol. 40, pp. 667- 674 ,(1995) , 10.1002/JNR.490400512
Helga J.J van Oers, E.Ronald de Kloet, Seymour Levine, Early vs. late maternal deprivation differentially alters the endocrine and hypothalamic responses to stress. Developmental Brain Research. ,vol. 111, pp. 245- 252 ,(1998) , 10.1016/S0165-3806(98)00143-6