Revisiting the Cholinergic Hypothesis in Alzheimer's Disease: Emerging Evidence from Translational and Clinical Research

作者: M. R. Farlow , M.-M. Mesulam , A. Vergallo , Harald Hampel , Z. S. Khachaturian

DOI: 10.14283/JPAD.2018.43

关键词: CholinesteraseNeuroscienceNeurodegenerationCerebral cortexDiseaseCholinergicMedicineNeurologyAtrophyNeuroimaging

摘要: Scientific evidence collected over the past 4 decades suggests that a loss of cholinergic innervation in the cerebral cortex of patients with Alzheimer's disease is an early pathogenic …

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