A study of atherosclerosis regression in Macaca mulatta

摘要: Abstract Rhesus monkeys were fed an atherogenic diet containing 40% of calories from lard and 1.0 mg/Cal cholesterol for either 19 months (Colony I) or 38 II). At the end induction period animals each colony divided into three groups (A, B, C) on basis total plasma concentration during period. Group A killed at baseline observation extent severity atherosclerosis. B was a which maintained mean concentrations between 280 to 320 mg/dl comparable human beings with modest hyperlipoproteinemia. C 180 220 mg/dl, people who had hyperlipoproteinemia but able reduce by approximately 100 using drugs. Each group further two subgroups (B1, B2, C1, C2). Animals subgroup 1 these diets 24 2 same 48 months. This report describes clinical history, chemical analyses arteries morphological atherosclerosis in both colonies