Slowing of M1 oscillations in brain tumor patients in resting state and during movement

摘要: Abstract Objective Brain tumors may severely disrupt the structure and function of brain. While abnormal low-frequency activity can be found around tumor borders, disrupted structural connectivity also impinge on neural in distant brain regions other frequency bands. We investigated how glioma patients with normal motor functioning affects primary areas (M1). Methods Using magnetoencephalography 12 unilateral located central sulcus, we studied bilateral M1s resting state during movement focus motor-related mu (8–12 Hz) beta rhythms (15–30 Hz). Principal component analysis served to test for differences spectral content. Results A shift was towards lower frequencies M1 hemisphere compared healthy hemisphere, caused by an increase decrease power. This pattern observed both movement. Conclusions ‘slowing’ oscillations resembles findings monohemispheric stroke Parkinson’s disease. loss intra-cortical account these findings, possibly supplemented tumor-induced changes neurotransmitter systems. Significance Motor unaffected a oscillations.