Microarray dispensing with real-time verification and inspection

作者: Christopher T. Brovold , Mandel W. Mickley , Brian L. Ganz , John Andrew Moulds

DOI:

关键词: Artificial intelligenceComputer visionComputer scienceSurface (mathematics)SpottingLight sourceData analysis

摘要: A microarrayer for spotting solution onto a receiving surface in an automated microarray dispensing device. Elements of the invention include: at least one dispense head(6,40) (4A1-4E10), light source (13) capable illuminating surface, camera (12) operating conjunction with source. The is acquiring and transmitting image data to computer. computer programmed receive analyze it. then generates post analysis based on data. available improving surface. In preferred embodiment, includes information relating alignment, spot quality, identification information. preferred, alignment enables make automatic adjustments relative positions head increase accuracy spotting. quality identifies as pass or fail.

参考文章(43)
Francis M. Butterworth, Manohar Das, Continuous microbiotal recognition method ,(1998)
Robert B. Silver, Analytical imaging system and process ,(1996)
Leonid Strinkovsky, James C. Herriman, Robert Tjon-Fo-Sang, Laurie J. Mango, Mark R. Rutenberg, Device and method for facilitating inspection of a specimen ,(1996)
Robert A. Hallowitz, Chester F. King, Method of and apparatus for automating detection of microorganisms ,(1999)
Mikel D. Rosenlof, Robert C. Schmidt, Shih-Jong J. Lee, Chih-Chau L. Kuan, Method and apparatus for detecting a microscope slide coverslip ,(1995)