作者: Gregory J. Archambeau , Anthony B. Wood , Richard L. Watson
DOI:
关键词: G protein-coupled receptor 、 Tight junction 、 Cell junction 、 Membrane potential 、 Biology 、 Membrane protein 、 Receptor 、 Intracellular signal transduction 、 Membrane 、 Biochemistry
摘要: Provided are electrokinetically-altered fluids (e.g., gas-enriched oxygen-enriched) electrokinetic fluids) comprising an ionic aqueous solution of charge-stabilized oxygen-containing nanostructures in amount sufficient to provide, upon contact with a cell, modulation at least one cellular membrane potential and conductivity, therapeutic compositions methods for using same treating digestive disorders or symptom thereof. The fluid include ioinic optionally combination other agents. Particular aspects provide regulating modulating intracellular signal transduction associated said by membranes, potential, proteins such as receptors, including but not limited G-Protein Coupled Receptors (GPCR), intercellular junctions tight junctions, gap zona adherins desmasomes). Other embodiments particular routes administration formulations the compositions.