Compositions and methods for treating digestive disorders

作者: Gregory J. Archambeau , Anthony B. Wood , Richard L. Watson

DOI:

关键词: G protein-coupled receptorTight junctionCell junctionMembrane potentialBiologyMembrane proteinReceptorIntracellular signal transductionMembraneBiochemistry

摘要: Provided are electrokinetically-altered fluids (e.g., gas-enriched oxygen-enriched) electrokinetic fluids) comprising an ionic aqueous solution of charge-stabilized oxygen-containing nanostructures in amount sufficient to provide, upon contact with a cell, modulation at least one cellular membrane potential and conductivity, therapeutic compositions methods for using same treating digestive disorders or symptom thereof. The fluid include ioinic optionally combination other agents. Particular aspects provide regulating modulating intracellular signal transduction associated said by membranes, potential, proteins such as receptors, including but not limited G-Protein Coupled Receptors (GPCR), intercellular junctions tight junctions, gap zona adherins desmasomes). Other embodiments particular routes administration formulations the compositions.

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